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肺复张策略在急性呼吸窘迫综合征患者机械通气中的应用研究 被引量:8

A clinical study of lung recruitment maneuvers in acute respiratory distress syndrome patients receiving mechanical ventilation
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摘要 目的:探讨急性呼吸窘迫综合征(ARDS)患者机械通气时应用肺复张策略的疗效与风险。方法:随机将ARDS患者分成两组:A组为对照组,B组为治疗组;两组均用PB840呼吸机采用Bilevel通气模式进行机械通气,原发病治疗相同;B组在A组的通气治疗基础上增加肺复张策略。记录开始前及24、48、72h的氧合指数(PaO2/FiO2)、二氧化碳分压(PaCO2)、是否出现气压伤并进行比对分析。结果:治疗组与对照组比较氧合指数12、24、72h均有明显改善,PaCO2在12、24、72h均有明显降低,而气压伤等并发症并无明显增加。结论:在ARDS机械通气患者中结合应用肺复张策略和Bilevel通气模式是安全有效的。 Objective: To discuss the effect and risk of the lung recruitment maneuvers in the acute respiratory distress syndrome (ARDS) patients. Methods:38 ARDS patients treated with the PB840 ventilator and with the same mode of Belevel were randomized into A and B groups.A group was the control group and the lung recruitment maneuvers have applied in the B groups.The oxygenation index and PaCO2 before and 24,48,72h after enrolling were measured and analyzed. And pulmonary barotrauma incidence were observed. Results: Compared with the control group,the oxygenation index had a significantly improvement and PaCO2 had a significantly decrease 24,48,72h after enrolling in the treatment group.However the pulmonary barotrauma and others complications did not increase.Conclusion: Combine the lung recruitment maneuvers with the mode of Belevel may be safe and effective at the ARDS patients receiving mechanical ventilation.
出处 《中国医药导报》 CAS 2007年第09Z期23-25,共3页 China Medical Herald
关键词 呼吸窘迫综合征 通气模式 机械通气 肺复张策略 Respiratory distress syndrome(RDS) Mode of ventilation Mechanical ventilation Lung recruitment maneuvers
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  • 1Bone RC, Balk R, Slotman G, et al. Adult respiratory distress syndrome, sequence and importance of development of multiple organ failure. Chest, 1992, 101: 320. 被引量:1
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