摘要
目的:探讨宫颈上皮内瘤变(CIN)及鳞状细胞癌(鳞癌)活检、锥切或全子宫切除术后病理分级及转化。方法:对2003年1月至2006年9月CIN及鳞癌病例,行不同诊治手段,对比分析病理分级及其转化。结果:经阴道镜活检,病理证实CIN 217例,平均年龄38.9岁;鳞癌62例,平均年龄53.3岁。其中继续锥切诊治63例,直接子宫全切54例。转阴率、分级转低率、分级不变率和分级转高率分别为14.5%、19.7%、59.0%和6.8%。结论:本组活检诊断与锥切术后病理分级符合率仅59.0%,说明CIN为多点病变,分级变异性较大,活检甚至锥切不能代表真实病变。而且子宫全切术后转阴率较低,且有6.8%的分级转高率。应注意加大锥切的范围,增加其诊疗效果。
Objective： To investigate pathological grade and transformation of patient with cervical intraepithelial neoplasia （CIN） and cervical squamous call Carcinoma （CSCC） treated by the cervix IMng specimen organization inspects （CLSOI）, the LEEP oonization or hysterectomy. Mothods：Collecting the CIN and CSCC continual cases of dinical pathology material from Jan. 2003 to Sep. 2006 and contrastively analyzed the different diagnosis methods and the pathological grade and transforms. Reaults：The pathology confirmed CIN 279 cases and CSCC 62 cases in the CLSOI by vaginoscope. The average age is 38.9 years in CIN, 53.3 in CSCC. There were 63 cases underwent further conization, and 54 cases directly received hysterectomy. The rate of transferring to negative, degrade, grade stable, and upgrade respectively was 14.5%, 19.7%, 59.0%, and 6.8% after conization or hysterectomy.Cortdumlorm：The patilological grading coincidence is only 59.0% between the CLSOI and oonization which means CIN is the multidrop lesion with great variability of pathological grade. CLSOI, even conization could not reflect the true pattlology. After hysterectomy, the rate transferring to negative is low, while 6.8% of upgrade. One should extend the scope of conization and improve therapeutic effect.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2007年第8期489-492,共4页
Journal of Practical Obstetrics and Gynecology
基金
河北省科技攻关计划项目资助(编号:05276101D-32)
关键词
宫颈上皮内瘤变
鳞癌
锥切
Cervical intraepithelial neopiasia
Cervical squamous call carcinoma
Conization
