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母乳中人巨细胞病毒的检测及哺乳期妇女感染状况的研究

Detecting HCMV-Ab in breast milk and HCMV infection patterns in bresat-feeding women
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摘要 用人巨细胞病毒(HCMV)单克隆抗体,对279例哺乳期妇女的乳汁进行了检测。结果表明:长春市城区母乳中HCMV-IgG抗体的阳性率为77.1%,HCMV-IgM抗体的阳性率为14%,其中包括13例HCMV-IgG、HCMV-IgM抗体均阳性,阳性率为4.7%。城区哺乳期妇女HCMV潜伏感染率为74.9%,原发感染率为11.5%,再发感染率为4.7%,后两者比较差异非常显著(χ2=139.8,P<0.001)。提示,长春城区母乳HCMV-IgM阳性率比我国部分地区低,哺乳期的感染以原发感染为主。 specimens of human milk were detected by HCMV-IgG, HCMV-IgM McAb. The results showed that the positive rate of HCMV-IgG was 77 1%, and HCMV-IgM was 14 0%. There were 13 specimens with both HCMV-IgG and HCMV-IgM positive in all 279 specimens, the positive rate was 4.7%. And the infective patterns of latent infection, primary infection and recurrent infection were 74 9%, 11 5%, 4 7% respectively. The results suggest that the positive rate of HCMV-IgM is lower in our area than in Sichuan province. The main pattern was primary infection in breast-feeding women( X 2=139 8, P <0 001)
出处 《白求恩医科大学学报》 CSCD 1997年第2期161-162,共2页 Journal of Norman Bethune University of Medical Science
关键词 人巨细胞病毒 母乳 妇女感染 哺乳期 HCMV Breast-milk
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