摘要
目的观察曲马多用于子宫切除手术时超前镇痛的作用效果。方法80例ASAI-级择期行妇科子宫切除手术的患者,随机分为组和组,每组40例,组术前硬膜外注入曲马多1 mg/kg,用0.9%NS稀释3 ml,组注入0.9%NS 3 ml。分别记录术后1、2、3、4、6、12、24 h和48 h的视觉模拟评分(VAS),48 h小时曲马多使用量和不良反应。结果术后3、4、6、12、24 h的VAS组均低于组,术后48h组曲马多使用量低于组,恶心、呕吐不良反应也低于组。结论曲马多用于妇科子宫切除手术超前应用,能减少术后曲马多用量,减轻不良反应的发生并提高镇痛质量。
Objective To observe the preemptive analgesic effect of tramadol on hysterectomy. Methods Eighty paints （ASAⅠ- Ⅱ ） were randomly assigned into two groups. Patients in group Ⅰ （n=40） received epidural injection of tramadol （1mg/kg）,and those in group Ⅰ （n=40） were given epidural injection of 3 ml saline. Postoperative analgesia efficacy was assessed by visual analog scales （VAS） at 1, 2, 3, 4, 6, 12, 24 and 48h after surgery. Tramadol dosage and adverse effects were recorded at 48h after surgery. Results VAS was lower at 3,4,6,12,24 hours in group Ⅰ than group Ⅰ （P〈0.05）. The dosage of tramadol was less in group Ⅰ （623mg±34mg） than group Ⅰ （723±23mg,P〈0. 05）. The incidence of nausea and vomiting was less in group Ⅰ than group Ⅰ （P〈0.05）. Conclusion Tramadol can produce preemptive effect, reduce the dosage of tramadol and abate adverse effect.
出处
《西部医学》
2007年第5期908-909,共2页
Medical Journal of West China
