摘要
目的:探探讨在功能性消化不良(functional dyspepsia,FD)患者中心理状态变化,自主神经功能改变和胃电节律紊乱之间的相互关系.方法:按罗马Ⅲ标准前瞻性分析FD患者85例和正常人30例的HAMD他评抑郁量表,HAMA他评焦虑量表及SCL-90项症状自评量表,同步检测自主神经功能变化及胃电节律紊乱情况.结果:FD患者普遍存在心理状态异常及自主神经功能损害和胃电节律紊乱,与正常人相比均有显著性差异(P<0.01);心理状态变化对自主神经功能改变有关且影响很大(P<0.01,C=0.4908),后者对前者的改变及影响程度较低(P<0.05,C=0.2519):自主神经功能改变与胃电节律紊乱有关且相关性相同(P<0.01,C= 0.4279);心理状态异常与胃电节律紊乱相关性无统计学意义(P>0.05,C=0.1866).结论:FD患者心理状态异常与自主神经功能改变的关系最密切,自主神经功能变化与胃电节律紊乱之间有一定关系,心理状态异常与胃电节律紊乱之间无直接关系.
AIM： To study correlations of psychological and autonomic nerve changes and gastric electrical activity in functional dyspepsia （FD）.
METHODS： Eighty FD patients and 30 healthy normal individuals were tested using the Hamilton Depression （HAMD）, Hamilton Anxiety （HAMA） and SCL-90 scales and heart rate variability and electrogastrography.
RESULTS： The FD patients showed some abnormalities in psychology, autonomic nerve and gastric electrical activity, demonstrating more obvious changes than normal people （P 〈 0.01）. The influence of psychological change on the autonomic nerve was greater and had more oscillation （P 〈 0.01, C = 0.4908） than that of the autonomic nerve on psychological state （P 〈 0.05, C = 0.2519）. The influences of autonomic nerves and gastric electric activity were equal （P 〈 0.01, C = 0.4279）. There was no relationship between psychological change and gastric electric activity （P 〉 0.05, C = 0.1866）.
CONCLUSION： FD patients were more influenced by psychological changes affecting the autonomic nerve than were healthy normal individuals. Changes of the autonomic nerve and gastric electric activity were related, whereas psychological changes and gastric electric activity were not directly related.
出处
《世界华人消化杂志》
CAS
北大核心
2007年第18期2063-2066,共4页
World Chinese Journal of Digestology
关键词
心理状态
自主神经
胃电节律
功能性消化不良
Psychology
Autonomic nerve
Gastric electric activity
Functional dyspepsia
