摘要
目的:探讨卒中危险因素暴露和聚集对脑血管血流动力学(CVHI)检测各指标及总积分的影响。方法:以整群抽样的方法抽取上海市南汇区40岁及以上的人群11 651例,进行卒中危险因素的调查,检测CVHI指标,对检测指标进行积分,分析不同卒中危险因素暴露水平间CVHI各检测指标和总积分的差异。结果:无危险因素暴露、单因素、2因素和多因素组的CVHI总积分分别为(84.3±22.1)、(67.4±28.5)(、66.1±29.3)(、61.5±29.9),随着危险因素的暴露和聚集程度的增加而显著下降;在CVHI各检测指标中,平均血流速度(Vmean)、最大血流速度(Vmax)、最小血流速度(Vmin)以及舒张压与临界压的差值(DP)等反映脑血流指标的测定值随着危险因素的暴露和聚集增加呈显著下降趋势,而脉搏波速(WV)、外周阻力(RV)、特异性阻抗(Zcv)、动态阻力(DR)、临界压水平(CP)等反映血管功能的指标则呈显著升高趋势。卒中危险因素聚集和CVHI受年龄因素影响,男性危险因素的暴露和聚集程度高于女性。结论:危险因素暴露和聚集与CVHI变化及其总积分降低密切相关,CVHI积分可能是综合评估卒中风险的良好指标。
Objective. To probe into the effect of store risks factor exposure and cluster on cerebral vascular hemodynamic indexes（CVHI） and its integrate score. Methods： 11 651 participants aged ≥40 years were cluster sampled from a community based population in Fengxian county of shanghai city. Risk factors survey and CVHI examination were performed and CVHI integrate score were calculated. Differences of CVHI and its integrate score between each exposure level were compared. Results： CVHI score in non exposure group, single risk factor,two risks and multi risks group were （84. 3±22. 1）, （67.4±28.5）, （66. 1±29. 3）, （61.5±29. 9）, respectively, and it presented decreasing trend. Vmean,Vmax, Vmin and DP were decreasing as risk factor exposure level elevating, but WV,RV,Zcv,DR and CP were increasing. Risk factors exposure and cluster were also associated with age and sex, exposure level and cluster in male were significantly higher than that in females. Conclusion. Associations between stroke risk factor exposure,cluster and CVHI change, integrate score decreasing are significant. CVHI score may be the ideal index for evaluating risk of stroke synthetically.
出处
《海南医学院学报》
CAS
2007年第4期383-386,共4页
Journal of Hainan Medical University
基金
上海市科专项(沪科合99第005号)资助项目
