摘要
目的分析白塞病血管受累的临床特点。方法总结53例血管受累的白塞病患者的临床资料。结果在348例白塞病患者中,血管受累者53例(15.2%)。男45例,女8例。主要表现深静脉血栓29例(54.7%)、动脉瘤22例(41.5%)、动脉狭窄17例(32.1%)等。全部患者均采用激素治疗,4例进行冲击治疗,45例合并使用免疫抑制剂;9例置入带膜支架,8例次效果满意,1例在6个月后再次出现动脉瘤;3例行主动脉换瓣术,2例出现术后瓣周漏。本组治疗好转39例(73.6%),恶化10例(8.9%),死亡4例(11.3%),2例死于非动脉瘤破裂,2例死于急性肺栓塞。结论白塞病累及血管的表现多种多样;男性多见;需要介入或者手术治疗者,应在白塞病不活动时进行;介入或手术治疗的效果与全身白塞病的活动性有关。肺动脉受累是有血管受累的白塞病患者死亡的独立危险因素。
Objective To analyze the clinical characteristics of the patients of Behcet＇s disease with vascular involvement. Methods Patients diagnosed as Behcet＇s disease with vascular involvement in Peking Union Medical College Hospital from 1990 to 2006 were included in this analysis. Clinical Characteristics were studied retrospectively. Results Fifty-three patients （15.2%）were included. The ratio of male vs female was 5.6：1. Vascular involvement included vein thrombesis（54.7%）,arterial aneurysms （41.5%） and artery stenosis （32,1%）.The most common manifestation of vascular involvement was deep vein thrombosis in lower extremities. The effect of intervention treatment or operation was related to the activity of Behcet＇s disease. The involvement of pulmonary artery was an independent correlative factor of mortality. Conclusions The manifestation of vascular involvement in Behcet＇s disease is various. Vascular involvement is more common in males. If needed, the intervention treatment or operation should be performed when the Behcet＇s disease is stable. The involvement of pulmonary artery is an independent correlative factor of mortality.
出处
《北京医学》
CAS
2007年第8期452-454,共3页
Beijing Medical Journal
关键词
白塞病
血管受累
临床特点
Behcet＇s disease（BD） Vascular involvement clinical Characteristics
