摘要
目的探讨血清和腹腔液IL-18、CA125水平的变化与子宫内膜异位症的关系。方法收集45例子宫内膜异位症患者血清和腹腔液,分别测定IL-18及CA125水平。结果子宫内膜异位症组腹腔液中IL-18水平明显高于对照组(P<0.05),在子宫内膜异位症组中腹腔液IL-18水平显著高于血清中水平(P<0.05),子宫内膜异位症I～IV期之间血清和腹腔液中IL-18水平无明显差异(P>0.05),子宫内膜异位症组患者血清CA125水平明显高于对照组,子宫内膜异位症I￣IV期中前3期术前血清CA125水平之间比较无显著性差异(P>0.05)。结论IL-18在子宫内膜异位症的发病机制中有重要作用,综合分析血清和腹腔液CA125、IL-18水平,对子宫内膜异位症的诊断有重要参考价值。
Objective To explore the relationship between the level IL-18 and CA 125 of serum and peritoneal fluid and EMs. Methods Serum and peritoneal fluid of Forty-five patients were obtained before and during surgery procedures, and then IL-I 8 and CA 125 respectively levels were measured. Results Peritoneal fluid IL-18 concentrations of EMs were statistically significantly higher than the control group. The concentrations of IL-18 in peritoneal fluid were statistically significantly higher than the serum in EMs. Peritoneal fluid IL-18 concentrations of EMs from stage I to IV were no significant difference. Serum CA125 concentrations of EMs were statistically significantly higher than the control group. Serum CA125 concentrations of EMs from stage I to stage m were no significant difference. Conclusion IL-18 may play an important role in the pathogenesis of the diease.To measure serum and peritoneal fluid CA125 concentrations blinding with serum and peritoneal fluid IL-18 concentrations has important referent value for EMs diagnosis.
出处
《中国现代医生》
2007年第08X期18-19,43,共3页
China Modern Doctor
