摘要
目的探讨复发性骨巨细胞瘤的手术治疗选择。方法回顾我院近3年收治的复发性骨巨细胞瘤23例,分析术后复发情况,评价关节功能。结果本组病例中,7例行再次病灶刮除植骨,13例行瘤段切除,3例行截肢。平均随访26.5个月,21例无复发,1例复发伴肺转移,1例死亡。瘤段切除病例中,10例行人工关节置换,2例行异体骨移植。对病灶刮除组、关节置换组和异体骨移植组进行Ennek-ing功能评分,分别为29.8、25.2和22分。病灶刮除组和异体骨移植组差异有统计学意义(P<0.05)。结论复发性骨巨细胞瘤首选病灶刮除。如存在病灶刮除反指征,则膝关节周围选择瘤段切除人工关节置换,腕关节周围选择带关节异体骨移植或同时合并关节融合。骨盆部位复发病例首选瘤段切除。
Objective To evaluate different choices of the surgical approach to recurrent giant cell tumors of bone. Methods In the recent 3 years,23 cases of recurrent giant cell tumor were overviewed retropectively. The recurrence rate and the function of adjiacent joint were analyzed. Results In this series,7 cases had curettage, 13 cases had wide resection and 3 cases had amputation. All patients had been followed up for a meantime of 26. 5 months. There were only 1 case of recurrence with lung metatasis and 1 case of death. In the wide resection group, 10 cases were reconstruced with prosthetic replacement,and 2 cases with allograft. The enneking functional score of curettage group, prosthetic replacement group and allograft group were 29. 8, 25. 2 and 22 respectively. There had statistically difference between curettage group and allograft group （P〈0. 05）. Conclusion In recurrent giant cell tumors of bone,curettage method was recommended firstly. If there had any anti-index of curretage, lesions around the knee should be treated with wide resection and prosthetic replacement, and lesions around the wrist should be treated with wide resection and allograft with or without arthrodesis. Lesions located in the pelvis and sacrum should be treated with wide resection.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2007年第8期614-617,共4页
Cancer Research on Prevention and Treatment
关键词
骨巨细胞瘤
复发
手术
Giant cell tumor of bone
Recurrence
Surgery
