摘要
目的:探讨血液灌流加血液透析对慢性肾衰患者血清中瘦素(Leptin)、同型半胱氨酸(tHcy)及甲状旁腺素(iPTH)的清除作用,并与单纯血液透析清除Leptint、Hcy、iPTH的效果比较。方法:在25例慢性肾衰患者常规血液透析中增加一次血液透析加灌流治疗,在透析及透析加灌流前后分别检测其Leptint、Hcy、iPTH血清水平,结果表明血透加灌流治疗后较治疗前明显降低(P<0.01),且较单纯血液透析明显降低(P<0.05),而单纯血液透析前后血清Leptint、Hcyi、PTH水平没有改变(P>0.05)。结论:血液灌流可以明显降低慢性肾衰患者血清中的Leptin、tHcyi、PTH水平,从而改善透析患者的生活质量,减少营养不良、心血管疾病和肾性骨病和异位钙化并发症的发生。
Objective： To study the clearing effects about hemoperfusion associated with hemodialysis on parathyroid hormone （PTH）, Leptin and the plasma homocysteine（tHcy） in chronic hemodialysis patients. Methods： 25 patients with chronic renal failure（CRF） were received hemoperfusion in combination with hemodialysis （HD＋ HP）. PlasmaPTH,Leptin and the plasma homocysteine（tHcy） were measured in plasma in pre and post-treatment by means of radio immunoassay. Conclusion： blood purification with hemoperfusion plus hemodialysis may decrease plasma PTH, Leptin and the they level more efficiently than henmodialysis performed alone.
出处
《河北北方学院学报（医学版）》
2007年第4期13-15,共3页
Journal of Hebei North University:Medical Edition
