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食管鳞癌组织中Langerhans细胞水平及意义 被引量:1

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摘要 采用免疫组化SP法检测39例正常食管上皮、23例不典型增生及39例食管鳞癌组织中S-100蛋白的表达,以观察其中Langerhans细胞(LC)的水平。结果正常食管上皮、癌旁不典型增生和鳞癌组织中LC阳性率分别为64.10%、30.43%、41.03%,P<0.05。高、中、低分化鳞癌中LC阳性率分别为77.78%、45.45%、21.05%,P<0.01;侵犯浅肌层、深肌层和纤维膜的鳞癌中LC阳性率分别为33.33%、40.00%、42.86%,P<0.05;无和有淋巴转移的鳞癌中LC阳性率分别为53.85%、15.38%,P<0.01。认为鳞癌中LC数量减少;LC数量减少程度与食管鳞癌的分化程度及是否发生淋巴转移有关,而与浸润深度无关。
出处 《山东医药》 CAS 北大核心 2007年第21期55-56,共2页 Shandong Medical Journal
基金 教育部"十五" "211工程"重点学科建设项目(教重办(2002)第2号)。
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