摘要
目的:探讨药源性死亡的特点和预防方法。方法:检索1994~2006年CHKD期刊全文数据库报道的药物不良反应致死亡病例,并进行统计、分析。结果:男性多于女性;呼吸、循环、消化系统疾病为主要原发疾病;抗微生物药、中枢神经系统药和中药为主要药物;静滴和口服为主要给药方式;过敏性休克为主要死亡原因。结论:临床医师、药师应重视药物不良反应,做到用药安全、有效。
Objective: To analyze the characteristics of drug-reduced death and try to find some methods to prevent it. Method: All the literatures about cases of drug-reduced death were studied in medical periodicals from 1994 to 2006. Result: Among the deaths the males were more than the females; microbicide, CNS drug, intravenous dripping and oral administration were the leading causes to lead to death. Allergic shock was also the common mortality. Conclusion: ADRs should be reconstructed to use these drugs safely and effectively.
出处
《药物流行病学杂志》
CAS
2007年第4期223-225,共3页
Chinese Journal of Pharmacoepidemiology
关键词
药源性疾病
药物不良反应
过敏性休克
死亡
Drug-induced Disease
Adverse drug reactions
Anaphylactic shock Death