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吡噻旺钠的制备及处方设计

The Prescription Design and Clinical Trall of MPO-Na
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摘要 合成了吡噻旺钠,并将其配成1%的稀醇液,考察了其在该溶液中的稳定性,测得该处方中吡噻旺钠的t0.9为1.81a。 To cbtain more potent and wide-spectrum agent, 2-mercaptopyridinai 1-oxidesodium (MPO-Na,I) was, synthesized, the minimum inhibitory concentrations of this compoundagainst 12 mycotic stiams were 0.25-10 pprn. The t0.9 of MPO-Na (1%) in the solution ofalcohol (40%) was 1.81 year. 56 patients were involved in the trail of MPO-Na (1%) solution,the total effective rate was 94. 64%.
出处 《现代应用药学》 CSCD 1997年第2期46-47,共2页
关键词 吡噻旺钠 制备 处方设计 稳定性 抗菌剂 MPO-Na stability MIC effective rate
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