摘要
合成了吡噻旺钠,并将其配成1%的稀醇液,考察了其在该溶液中的稳定性,测得该处方中吡噻旺钠的t0.9为1.81a。
To cbtain more potent and wide-spectrum agent, 2-mercaptopyridinai 1-oxidesodium (MPO-Na,I) was, synthesized, the minimum inhibitory concentrations of this compoundagainst 12 mycotic stiams were 0.25-10 pprn. The t0.9 of MPO-Na (1%) in the solution ofalcohol (40%) was 1.81 year. 56 patients were involved in the trail of MPO-Na (1%) solution,the total effective rate was 94. 64%.