摘要
目的:观察经皮椎体内注入骨水泥(聚甲基丙烯酸甲酯)治疗脊椎骨质疏松压缩性骨折的疗效。方法:自2005-06/2006-06吉林大学中日联谊医院骨科及大庆龙南医院骨科对35例40个椎体的骨质疏松压缩性骨折患者使用经皮椎体内注射骨水泥,行椎体成形术。成形材料:美国KYPHON公司生产的骨水泥,生产准许号:(GB/T19001-2000和YY/T0287-1996)。结果:35例患者均参加随访6个月。术后均未出现骨水泥外漏、脊髓或马尾神经损伤等并发症。35例患者中5例出现穿刺部位局部疼痛,服用镇痛药物后均缓解。疼痛完全消失25例,占71.4%;明显缓解8例,占22.6%;轻度缓解2例,占6.0%;无缓解0例。15例患者在术后72h内均能下床活动。术后未再发生压缩性骨折及疼痛。结论:经皮椎体注入骨水泥可以有效改善椎体骨质疏松压缩性骨折患者疼痛症状,随访6个月未出现充填剂不良性宿主反应,临床疗效较好。
AIM： To evaluate the therapeutic effects of percutaneous bone cement （polymethyl methacrylate） vertebroplasty in the treatment of osteoporotic compression fractures.
METHODS： Thirty-five patients （40 vertebra） with vertebral osteoporotic compression fractures were treated with percutaneous polymethylmethacrylate vertebroplasty in Department of Orthopedics, China-Japan Union Hospital of Jilin University, and Daqing Longnan Hospital. The cement was product of KYPHON （U.S. No. GB/T19001-2000 and YY/T0287-1996）.
RESULTS： All the 35 patients were followed up for 6 months. None of them experienced cement extravasation, injury of spinal cord and nerve roots or other severe complications after treatment. Among the 35 cases, 5 had pains in puncture s＇rtes, and relieved by painkiller; 25 （71.4%） had complete relief, 8 （22.6） were significantly relieved, 2 （6.0%） were mildly relieved, and 0 had no relief. Moreover, 15 cases could get up and move within 72 hours after the surgery. No further vertebral compressions or pains reoccurred postoperatively.
CONCLUSION： Percutaneous pelymethylmethacrylate vertebroplasty can effectively improve the pain in patients with osteoporotic compression fractures of vertebra. During the 6 months follow-up, no adverse host response in filler is found, and the clinical effect is good.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2007年第32期6484-6486,共3页
Journal of Clinical Rehabilitative Tissue Engineering Research
