摘要
目的:建立肠泰胶囊的质量控制方法。方法:采用了白花蛇舌草、肿节风的薄层色谱,白头翁的紫外可见分光光度法进行定性鉴别;并采用醇浸出物测定法进行含量测定,装量差异、水分、崩解时限及微生物限量检测。结果:白头翁对照药材提取液与供试品提取液均在(201±1)nm波长处有最大吸收,紫外吸收光谱基本一致,白花蛇舌草、肿节风的提取物的TLC结果与对照品一致,样品的醇溶性浸出物平均含量为38.8 mg/ g,装量差异、水分、崩解时限及微生物限量检测均符合药典规定。结论:该质控方法简便,可靠。
Objective：To establish a quality control method for Changtai capsules. Methods：Qualitative analysis of Hedyotis difusa Willd and Herba Sarcandrae were carried out by TLC,Radix Pulsatillae was tested by UV. Ethanol-soluble extractive of Changtai capsule was determined by Chinese Pharmacopoeia. Results ：The extracting solution of the Radix Pulsatillae and it＇s masculine comparison have the biggest absorption in （201± 1 ） nm, and have the same UV -spectrum. The extractive of Hedyotis difusa Willd and Herba Sarcandrae were assayed by TLC. The results were consistent with the controles. The average content of ethanol-soluble extractive of the samples was 38.8 mg/g. The weight variation, water content, disintegration time, microbiological timiting, test conformed with Chinese pharmacopoeia. Conclusion：This method is simple, accurate, and can be used as the quality control of Changtai capsules.
出处
《药学实践杂志》
CAS
2007年第4期224-226,共3页
Journal of Pharmaceutical Practice
