摘要
目的:探讨血尿酸、C-反应蛋白与冠状动脉病变关系。方法:将176例行冠状动脉造影患者分为冠状动脉病变组(Ⅰ组)和非冠状动脉病变组(Ⅱ组),分别检测血清尿酸和C-反应蛋白浓度,观察变化规律,探讨血清尿酸、C-反应蛋白与冠状动脉病变关系。结果:Ⅰ组血清尿酸、C-反应蛋白明显升高,并且血清尿酸、C-反应蛋白与冠状动脉狭窄病变Gensini积分明显相关(r分别为0.38,0.42,P<0.01)。结论:冠状动脉病变患者血清尿酸、C-反应蛋白明显增高,血清尿酸、C-反应蛋白在冠状动脉病变发生发展中起重要作用。
Objective：We study on the relationship among the concentration of serum uric acid,the concentration of serum C-reactive protein and the severity of coronary lesions. Methods：176 patients were divided into two groups （group Ⅰ ：coronary artery lesions group and group Ⅱ ：non-coronary artery lesions group） by coronary angiography,the concentration of serum uric acid and serum C-reactive protein were measured in each patients, the relationship among the severity of coronary lesinns and the concetration of serum uric acid,the concetration of serum C-reactive protein were analysed by liner-correlated analysis. Results： the concentration of serum uric acid and serum C-reactive protein were increased in the groupⅠ , the concetration of serum uric acid and serum C- reactive protein correlated with Gensini scores. Conclusion：The results suggest that the increased serum uric acid and C-reactive protein play important role in the formation and development of coronary artery disease.
出处
《重庆医科大学学报》
CAS
CSCD
2007年第9期954-955,973,共3页
Journal of Chongqing Medical University
基金
重庆市卫生局科研基金资助项目(渝卫科教2005-31)
重庆市自然科学基金(项目编号:CSTC2006BB5280)
关键词
冠状动脉病变
尿酸
C-反应蛋白
冠状动脉造影
Coronary artery lesion
Uric acid
C-reactive protein
Coronary angiography
