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脑动静脉畸形超微病理与临床症状的关系 被引量:10

Rel ationship of ultrapathol ogy and clinical manifestation in cerebral arteriovenous mal formation
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摘要 对66例不同临床表现脑动静脉畸形的血管组织进行了光镜和电镜观察,探讨了该病临床表现与病理组织学的关系。研究结果提示:以出血为首发症状的多为中小型脑动静脉畸形,其超微病理表现为血管内膜变性坏死、弹力板严重损伤、引流静脉管腔狭窄或闭塞;而以癫痫发作为首发症状的大型AVM则主要表现为血管内膜增生、弹力板轻度损伤。 Cerebral arterioneous malformations (AVM ) give great varity to clinical presentations and vascular characteritics. The relationship of vascular feature of AVM to clinical manifestation has been reported by several authors , but study of clincal findings of AVM associated with its ultrami- cropathology is needed. Histopathological features with light and electron microscopy in 66 AVM cas- es with different clinical manifestations were observed. The histopathological characteristics of AVM itn relation with its clinical finditngs was discussed. ln conclusion , the results that presenting with hem- orrhage was often related to mid or small AVM , its ultramicroscopy showed internal elastic membrane severely injured , membrane was degernerated and necrotic , and the vascular lumen was narrow and obliterated. The presenting symptnms with seizure has great proliferation of the thicking of the inti- ma , and the elastic memhrane was mildly injured. Pathogeotesis and mechanism of cerebral AVM were discussed according to its ultrapathplogy.
出处 《北京医学》 CAS 北大核心 1997年第1期3-5,共3页 Beijing Medical Journal
关键词 脑动静脉畸形 超微病理 临床 Cerebral arteriovenous malformations Ultrapathology Clinical
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