摘要
目的:建立降压益肾颗粒的质量标准。方法:用TLC法对降压益肾颗粒中鬼针草、制首乌、山茱萸、玄参、川牛膝进行定性鉴别;用UV法测定制剂中总黄酮(芦丁)的含量。结果:TLC特征明显,阴性对照无干扰,专属性强;总黄酮(芦丁)在0.04～0.60mg·mL^(-1)浓度范围内与吸光度呈良好线性关系(r=0.9999);平均加样回收率为101.6%,RSD=2.41%。结论:所建标准可用于降压益肾颗粒的质量控制。
OBJECTIVE： To establish the quality standard for Jiangyayishen granula. METHODS： Spanishneedles Herb, Radix Polygoni Multiflori, Fructus Corni, Radix Scrophulariae, and Radix Cyathulae were identified by TLC; and the contents of Total flavonoids （Rutin） were determined by UV spectrophotometry. RESULTS： The TLC characteristics were distinctive and specific, and there was no interference in negative control. The linear concentration range of Total flavones（Rutin） was 0.04-0.60mg·mL^-1（ r = 0.999 9） and the average recovery was 101.6%, RSD = 2.41%. CONCLUSION ： The established standard can be used for the quality control of Jiangyayishen granula.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第21期1643-1645,共3页
China Pharmacy
