摘要
目的 掌握山东省克山病病情现状，了解内外环境硒营养水平，指导防治科研工作。方法 选择5个病区县的8个自然村，每村对100名左右村民进行临床查体和心电图描记，可疑心脏异常者行X线胸部摄片，同时采集当地部分居民食用粮和头发样品检测含硒量。结果 克山病总检出率为5．51％，无性别差异；异常心电图检出率为24．28％，异常心电图分类潜在型患者以束支和房室传导阻滞、频发室性早搏、ST—T及T波改变为多见，而慢型患者以心房纤颤、左室肥大、心肌损害为主；拍摄X线胸片的43例可疑患者，心脏增大者16例；头发含硒量为（0．334±0．652）mg／kg，小麦、玉米、瓜干含硒量分别为（0．027±0．006）、（0．022±0．007）和（0．018±0．005）mg／kg。结论 目前山东省克山病病情处于稳定水平。病区居民头发含硒量呈上升趋势，但外环境粮食硒仍处于较低水平。
Objective To investigate the incidence of Keshan disease （KSD） and the in vivo environmental selenium （Se） level of in Shandong Province and scientific to guide the research, prevention and control work. Methods 8 villages were selected in 5 KSD areas, out of each 100 villagers were clinically examined and underwent electrocardiogram （ECG）. The suspicious people were taken chest X-ray radiographs, and their hair and wheat, corn and potato were collected to examine the Se nourishment level. Results The detective rate of KSD was 5.51% and it was not significant different （P 〉 0.05） between the male and the female. In the 788 ECG traced, the abnormal rate of ECG was 24.62%. In the 44 KSD patients, potential patients present such abnormal ECGs as right bundle block, 1-degree atrioventricular block, frequent premature ventricular contractions, left anterior fascicular block, ST-T and T wave changes, while chronic patients did atrial fibrillation, left ventricular hypertrophy and myocardial damage. Out of 43 suspicious who took X-ray, 16 cases were cardiac enlarged, 10 enlarged mildly and 6 moderately. The Se content of hair was （0.334 ± 0.652）mg/kg, the Se content in wheat, corn and potato was（0.027 ± 0.006）, （0.022 ± 0.007）mg/kg and （0.018 ± 0.005）mg/kg respectively. Conclusions The condition of KSD in Shandong Province is currently steady. Se level goes up in their hair, but still stays relatively low in their food.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2007年第4期418-420,共3页
Chinese Jouranl of Endemiology
关键词
克山病
调查
心电描记术
X线
硒
Keshan disease
Surveys
Electrocardiography
X-rays
Selenium
