摘要
目的：探讨3.0T MRI高分辨多序列成像对颈动脉斑块的定位和分型能力。方法：31例经超声筛选的颈动脉斑块患者，在3.0T磁共振仪上，采用相控阵颈部线圈和心电门控，行3D-TOF、T1WI、T2WI和PDWI横断面扫描，在颈总动脉、分叉部及颈内动脉3个部位，对斑块进行初步定性和分型。结果：25例共150个血管断面中，Ⅰ-Ⅱ型占34%，Ⅲ型占44.7%，Ⅳ-Ⅴ型占14%，Ⅵ型占3.3%，Ⅶ型占4.0%；Ⅶ型的钙化斑块均被CT所证实。不同类型斑块在颈动脉各部位的分布上差异无显著性意义（P=0.112）。Ⅵ型病例近期均有同侧大脑半球颈动脉供血区缺血事件发生。结论：在3.0T MR上应用高分辨多序列技术能清晰显示颈动脉血管壁的细微结构和斑块的形态特征，对进展期斑块具有准确定位和初步分型能力，可作为一项无创性评价颈动脉粥样斑块的理想方法。
Objective：To study the capability of detecting the distribution and classification of carotid atherosclerotic plaque using high resolution multiple sequences imaging with 3.0T MR scanner. Methods.. Thirty-one patients with atherosclerosis which detected by duplex ultrasound underwent bilateral carotid artery MRI with a 3.0T scanner. Phase-array coil of neck and ECG gating were used. The pulse sequences included T1WI,T2WI, proton density and 3D time of flight. American heart association classification criteria was modified for MRI diagnosis and was used to evaluate lesions quantitatively and quailitatively at 3 key-points （common,internal and bifurcation of carotid artery） for classification. Results： Of the 25 patients with 150 key-points at axial plane examined,Type Ⅲ （44.7%） occurred most commonly,followed by Types Ⅰ- Ⅱ （34%） ,Types Ⅳ - Ⅴ （14%） ,Type Ⅵ （3.3%） ,and Type Ⅶ （4.0%）. Calcified plaques in Type Ⅷ was all proved by CT images. There was no significant statistical difference in different types of carotid atherosclerosis （Fisher＇s exact test ： P = 0.1,12）. All of the type Ⅵ patients had ischemia recently in the area supplied by unilateral cerebral artery. Conclusion.. High resolution multi-sequence MRI with 3.0T scanner was able to clearly display the arterial wall structure and the morphology characteristics of atherosclerotic plaque,as well as able to accurately localize and classified advance atherosclerotic lesions. MRI with a 3.0T scanner is an optimal non-invasive approach in the evaluation of arteriosclerosis of carotid artery.
出处
《放射学实践》
2007年第7期698-701,共4页
Radiologic Practice
关键词
磁共振成像
颈动脉
动脉硬化
Magnetic resonance imaging
Carotid artery
Atherosclerosis
