摘要
在 2 7只新西兰白兔胸大肌瓣转移的动物模型上 ,进行原神经支配、失神经后舌下神经植入再支配的比较研究 ,术后 4周、8周、12周和 16周行大体观察、光镜观察、激发肌电、神经免疫组化、肌瓣肌纤维多种酶组织化学染色的肌纤维组化分型检查。结果表明 ,失神经胸大肌瓣可重获舌下神经再支配 ,并在舌下神经支配下行使收缩功能 ,肌纤维的组化型别发生改变 ,从以酵解型纤维为主转化为以氧化型纤维为主 ,呈镶嵌分布模式 ,而类似于舌下神经原支配的肌肉。神经肌肉蒂植入在发生神经再支配的时间及范围方面优于神经直接植入。
In order to investigate the morphological, electrophysiological and histochemical characteristics of the pectoralis major myoflaps with original nerve innervation and with hypoglossal nerve reinnervation, after denervation, the model of myoflap transposition to reconstruct the tongue was adopted on 27 New Zealand white rabbits. After the myoflaps were transferred, original nerve innervation (ON), hypoglossal genioglossus muscle branch nerve implantation (NI) and hypoglossal genioglossus muscle neuromuscular pedicle implantation (NMP) were performed. The flaps were examined at the intervals of 4,8,12 weeks and 16 weeks after operation. The results showed that the denervated myoflaps were reinnervated in NI and NMP, myoflaps contracted when the hypoglossal nerves were stimulated. The histochemical properties of muscle fibers changed. Some type Ⅱ fibers in the myoflaps transformed into type Ⅰ fibers, but the pattern of distribution of the muscle fibers displayed mosaic and was similar to that of genioglossus muscle. In terms of speed and scope of reinnervation, the NMP was superior to the NI.\;
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
1997年第1期7-10,共4页
West China Journal of Stomatology
关键词
胸大肌瓣
神经再支配
神经植入
舌下神经
舌缺损
pectoralis major myoflap\ \ reinnervation\ \ nerve implantation\ \ neuromuscular pedicle\ \ sublingual nerve
