摘要
以N-甲基乙酰胺、醋酸乙烯酯为原料,N,N-二甲氨基吡啶(DMAP)为催化剂,合成N-甲基-N-乙烯基乙酰胺。对影响反应的各种因素进行了考察,确定了最佳反应条件为:反应温度65℃,反应时间12h,催化剂与N-甲基乙酰胺物质的量比为0.55。在此条件下,N-甲基-N-乙烯基乙酰胺收率为87.6%,催化剂可回收套用12次。
N-Methyl-N-vinylacetamide was synthesized from N-methylacetamide and vinyl acetate with N,N-dimethylamino pyridine （DMAP） as catalyst. The factors influencing on the reaction were investigated,the optimum conditions were obtained as follows： the reaction temperature was 65℃ ,the reaction time was 12h, the mole ratio of catalyst to N-methylacetamide was 0.55. Under the above mentioned conditions, the yield of N-methyl-N-vinylacetamide was 87.6% , and the catalyst could be recycled for 12 times.
出处
《精细与专用化学品》
CAS
2007年第14期17-19,共3页
Fine and Specialty Chemicals
