摘要
目的:评价半剂量对比增强 MRI 对正常及异常垂体的显示能力。材料与方法:MR 检查61例垂体,包括9例正常垂体,37例垂体瘤(其中微腺瘤12例,大腺瘤25例;23例经手术证实,其余经临床实验室检查所证实),7例为垂体瘤手术后.2例γ-刀术后,尿崩症5例,原发性空蝶鞍1例。61例垂体中13例采用全剂量,48例采用半剂量增强检查。使用1.5T 机型,造影剂用量为0.05mmol/kg 或0.1mmol/kg,常规扫描技术如下:(1)矢状位定位像;(2)T_1WI 冠状位平扫;(3)静脉注射造影剂后立即行冠状位及矢状位扫描。结果:48例垂体半剂量检查均显示满意,10例微腺瘤中9例增强表现为不强化的局限性低信号灶,1例与垂体同等强化且边界不清;22例大腺瘤均显示较好,增强能明确肿瘤向周围的侵犯,并显示残存的正常垂体,为手术治疗提供方便。结论:对垂体微腺瘤及大腺瘤的检测,半剂量 Gd-DTPA 增强蝶鞍 MR 成像具有与全剂量相当的可比性,且造影剂费用相对减低,是一种临床实用的蝶鞍成像方法。
Objective:estimate the value of half-dose gadolinium enhanced MRI in normal and abnormal pituitary.Materials and Methods:61 cases of pituitary were analysed,including normal pituitary(n=9).adenomas(n=37)(12 microadenomas and 25 macroadenomas,23 cases were confirmed by surgery,and others by clinical or endocrinologic examination),post-operation(n= 7), postoperation of γ-knife(n=2),diabetics insipidus(n=5)and primary empty sella(n=1).13 cases of 61 were enhanced with full-dose Gd-DTPA,and the rest with half-dose.All MR examinations were performed at 1.5T,MRI evaluation of suspected ade- noma could be tailored to include:①a sagital scout localizer image,②a precontrast T_1-weighted coronal MR imaging and ③an im- mediated postcontrast T_1-weighted coronal and sagital MRI with 0.05 or 0.1mmol/kg Gd-DTPA.Results:48 patients were well demonstrated with half-dose.9 of 10 microadenomas were local hypointense lesions on enhanced images,and one was as isointense as the normal enhanted pituitary with obscure margin,22 macroadenomas were well demonstrated including extention and invasion of the surrouding structures,remnant pituitary tissue were visible too.Conclusion:It is suggested that a half-dose study is compa- rablc to that of full-dose,and cost of contrast material is reduced.
出处
《临床放射学杂志》
CSCD
北大核心
1997年第1期5-8,共4页
Journal of Clinical Radiology
关键词
半剂量
NMR
成像
垂体肿瘤
Gadolinium
Half-dose
MR Imaging
Neoplasm
pituitary