摘要
目的：比较醋柳黄酮与丹参治疗高脂、高粘血症病人的疗效。方法：治疗组３５例（全部男性，年龄５２±ｓ８ａ）用醋柳黄酮２０ｍｇ，ｐｏ，ｔｉｄ。对照组３４例（全部男性，年龄５１±９ａ）用丹参１０ｍＬ，ｐｏ，ｂｉｄ。疗程均为６ｗｋ。结果：治疗组血胆固醇（ＴＣ）、三酰甘油（ＴＧ）、载脂蛋白Ｂ１００（ＡｐｏＢ１００）、血浆凝血因子Ｉ、血液粘度、血小板聚集率和血栓指数均较治疗前有显著（Ｐ＜０．０５）或极显著（Ｐ＜０．０１）下降。对照组在１０·ｓ－１血液粘度较治疗前有极显著下降（Ｐ＜０．０１），在１００·ｓ－１血液粘度和血栓指数较治疗前有显著下降（Ｐ＜０．０５）。结论：醋柳黄酮治疗后，大部分指标（除１０·ｓ－１血液粘度指标外）下降，优于丹参。
AIM: To compare flavonippophae and Salvia miltiorrhiza in treating patients with hyperlipidemia and high blood viscosity. METHODS: Treatment group 35 patients (M 35, age 52±s 8 a) were treated with flavonippophae, 20 mg, po, tid for 6 wk. Control group 34 patients (M 34, age 51±9 a) were treated with Salvia miltiorrhiza 10 mL, po, bid for 6 wk. RESULTS: TC, TG, Apo B 100 , plasma thromboplastin factor I, blood viscosity, platelet aggregation and thrombus index in treatment group were decreased after treatment (P<0.01 or P<0.05). Blood viscosity and thrombus index in control group were decreased after treatment (P<0.01 or P<0.05). CONCLUSION: After treatment of flavonippophae most parameters (besides blood viscosity at shear rate 10·s -1 ) are better than that of Salvia miltiorrhiza.
出处
《新药与临床》
CSCD
北大核心
1997年第1期17-18,共2页
关键词
醋酸黄酮
丹参
高脂血症
高粘血症
flavonippophae
Salvia miltiorriza
platelet aggregation
blood viscosity
