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胺碘酮联合氯沙坦治疗高血压合并阵发性心房颤动 被引量:1

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摘要 目的研究氯沙坦对高血压合并阵发性心房颤动的影响及可能的机制。方法将63例患者分为治疗组与对照组,两组均口服胺碘酮,治疗组加用氯沙坦100mg/d,疗程12个月,对照组用长效硝苯吡啶25mg,每天2次,监测6个月、12个月心房颤动的复发率与6个月、12个月左心房内径值。结果治疗组治疗后6个月心房颤动复发率较对照组低,12个月后左心房内径小于对照组,以上两组比较差异有统计学意义(P<0.05)。结论胺碘酮联合氯沙坦治疗阵发性心房颤动能够减少心房颤动的发生,并能抑制左心房扩大。其机制可能与改善心房的组织重构有关。
出处 《临床医学》 CAS 2007年第6期32-33,共2页 Clinical Medicine
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