摘要
比较６９例冠心病患者多巴酚丁胺负荷９９ｍＴｃ甲氧基异丁基异腈（ＭＩＢＩ）心肌断层显像与８２例运动试验９９ｍＴｃＭＩＢＩ心肌断层显像的结果，以探讨它们对冠心病的诊断价值。结果表明：以冠状动脉造影结果为标准，多巴酚丁胺负荷诊断冠心病的敏感性和特异性分别为９１２％和８００％，运动试验分别为８９４％和８２９％。多巴酚丁胺负荷检出冠状动脉病变的敏感性和特异性：左前降支为７８１％和９１３％，回旋支为６６７％和９８２％，右冠状动脉为１００％和８３７％；运动试验分别为７８３％和９１１％，６００％和９６８％，９０９％和８５０％，差异均无显著性（Ｐ＞００５）。提示两者结果相近，对于不能进行运动试验的病人，多巴酚丁胺试验是一种有价值的诊断冠心病的方法。
PURPOSE To investigate the diagnostic value of dobutamine 99m Tc MIBI myocardial SPECT in coronary artery disease (CAD) METHODS Dobutamine stress 99m Tc MIBI myocardial SPECT (Dob ECT) in 69 patients and exercise stress 99m Tc MIBI myocardial SPECT (EST ECT) in 82 patients All patients underwent coronary angiography and significant coronary disease was defined as ≥50% luminal narrowing in a major artery RESULTS The sensitivity and specificity of Dob ECT for the detection of CAD were 91 2% and 80 0%, respectively The sensitivity and specificity of Dob ECT for the detection of individual coronary artery stenoses were 78 1% and 91 3% for left anterior descending, 66 7% and 98 2% for left circumflex and 100% and 83 7% for right coronary artery, while those of EST ECT were 78 3%,91 1%, 60 0%,96 8% and 90 9%,85 0%, respectively (P>0 05) CONCLUSIONS Dobutamine stress 99m Tc MIBI might be considered appropriate as a provocative test for detecting CAD when physical exercise cannot be carried out
出处
《中华核医学杂志》
CSCD
北大核心
1997年第2期88-90,共3页
Chinese Journal of Nuclear Medicine
关键词
多巴酚丁胺
心脏功能试验
mTc99
MIBI
冠心病
Coronary disease
Dobutamine
Heart function tests
Tomography
emission computed
single photonNitriles
