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肺泡Ⅱ型上皮细胞钠通道在肺水清除中信号转导的研究进展 被引量：7

Recent progresses of signal transduction in alveolar epithelial vectoral sodium and fluid transport via sodium channel of alveolar type Ⅱ cells
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摘要 肺泡Ⅱ型细胞上钠离子主动转运是肺泡内液体清除的主要机制，钠通道的活性是钠离子主动转运的关键。本文简要介绍细胞内信号转导通路对钠通道活性的调节。 Alveolar epithelial vectoral sodium and fluid transport via sodium channel of alveolar type Ⅱ cells,Na-channel activation plays a key role in stimulation of Na transport. This article briefly reviews the regulative mechanism of signaling pathways in Na-channel activation.
作者 何琳 李涛平
机构地区 南方医科大学附属南方医院急诊科
出处 《国际呼吸杂志》 2007年第12期919-921,共3页 International Journal of Respiration
关键词 肺泡Ⅱ型细胞 钠离子转运 信号转导 Alveolar type Ⅱ cells Sodium ransport Signal transduction
分类号 R563 [医药卫生—呼吸系统]
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参考文献23

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  • 3申海燕,李涛平.肺泡Ⅱ型细胞钠通道的生物学特点及调节机制[J].国外医学（呼吸系统分册）,2005,25(7):534-537. 被引量：6
  • 4Bronchiero E,Dgenais A,Prive A,et al. Evidence of a functional CFTR C1- channel in adult alveolar epithelial cells. Am J physiol Lung Cell Mol Physiol, 2004,287 : L382-392. 被引量：1
  • 5Lazrak A, Nielsen VO, Matalon S. Mechanisms of increased Na^+ transport in AT Ⅱ cells by cAMP: we agree to disagree and do mire experiments. Am J Physiol Lung Cell Mol Physiol, 2000,278 : 233-238. 被引量：1
  • 6O'Grady SM, Jiang X, Ingbar DH. C1- channel activation is necessary for stimulation of Na transpor in adult alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol,2000,278:239-244. 被引量：1
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二级参考文献15

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  • 8Scott MO,Jiang X,Ingbar DH,et al.Cl- channel activation is necessary for stimulation of Na transport in adult alveolar epithelial cells.Am J Physiol Lung Cell Mol Physiol,2000,278(2):L239-L244. 被引量：1
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  • 10Ahmed L,Nielsen VG,Matalon S.Mechanisms of increased Na+ transport in ATⅡ cells by cAMP:we agree to disagree and do more experiments.Am J Physiol Lung Cell Mol Physiol,2000,278(2):L233-L238. 被引量：1

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国际呼吸杂志
2007年 第12期

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