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鼻阻塞性疾病与阻塞性睡眠呼吸暂停低通气综合征的相关性研究 被引量:8

Study on the relationship between nasal disease and obstructive sleep apnea hypopnea syndrome
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摘要 目的探讨鼻阻塞性疾病与阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的关系。方法选用2001~2005年我科OSAHS手术病例132例,合并鼻阻塞性疾病的有36例,其中先行鼻部手术后行改良悬雍垂腭咽成形术者22例,设为分期手术组,同期手术者14例,设为同期手术组。结果①分期手术组鼻部手术以后Epworth嗜睡量表(Epworth sleepiness score,ESS)评分从(13.64±5.09)分降至(5.40±3.17)分,鼾声指数从(196.73±113.58)次/h降至(67.72±43.57)次/h,差异均有显著性(P<0.01),而呼吸暂停低通气指数(apnea and hypopnea index,AHI)和最低血氧饱和度(lowest oxygen saturation,LSaO2)在鼻部手术前后无明显差异(P均>0.1),其中19例行改良悬雍垂腭咽成形术,术后AHI、LSaO2、鼾声指数和ESS评分与术前比较,有显著差异(P均<0.01);②同期手术组手术前后AHI、LSaO2、鼾声指数和ESS评分有显著差异(P均<0.01)。结论①OSAHS患者的嗜睡和打鼾症状与鼻阻塞性疾病有关,鼻部手术可以解决;②OSAHS患者的AHI、LSaO2与鼻阻塞性疾病无关,应联合进行改良悬雍垂腭咽成形术治疗。 OBJECTIVE To observe the relationship between nasal obstructive disease and obstructive sleep apnea hypopnea syndrome (OSAHS). METHODS Thirty six cases combined with nasal obstructive diseases were chose for study from 132 OSAHS cases underwent H-UPPP in our department from 2001 to 2005. The patients were divided into 2 groups depending on whether the nasal and H-UPPP were done at the same time or not. Twenty two cases were operated on the nasal diseases first consisted of group 1. The left 14 cases were group 2. RESULTS (1) the ESS of group 1 dropped from (13.64±5.09) to (5.40±3.1) after nasal surgery only, and the snore index dropped from (196.73±113.58) to (67.72±43.57). There was a significant difference before and after operation in above two indexes (P〈0.01), while there was no difference in indexes of AHI and LsaO2. After H-UPPP, the significant difference was observed in all the 4 indexes in group 1. (2) There was a significant difference in snore index, AHI, ESS, LSaO2 before and after operation in group 2. CONCLUSION (1) The syndrome of sleepiness and snore are related to nasal obstructive diseases. And sleepiness can be resolved through nasal surgery. (2) The AHI, LSaO2 of the OSAHS patients have no correlation with nasal diseases. The nasal and pharyngeal surgery should be done simultaneously for treating OSAHS patients.
出处 《中国耳鼻咽喉头颈外科》 北大核心 2007年第6期379-381,共3页 Chinese Archives of Otolaryngology-Head and Neck Surgery
关键词 睡眠呼吸暂停 阻塞性 鼻疾病 耳鼻喉外科手术 打鼾:过度嗜睡性障碍 Sleep Apnea, Obstructive Nose Disease Otorhinolaryngologic Surgical Procedures Snoring Disorders of Excessive Somnolence
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  • 1殷善开,关建,曹振宇.阻塞性睡眠呼吸暂停低通气综合征的序列治疗[J].临床耳鼻咽喉科杂志,2003,17(12):765-767. 被引量:30
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