摘要
目的探讨颅内-外动脉粥样硬化性狭窄与冠状动脉狭窄的关系。方法将34例经冠状动脉造影证实为冠状动脉狭窄,并且同时行全脑血管造影的冠心病患者分成两组,A组(冠状动脉狭窄≤2支)18例,B组(冠状动脉狭窄≥3支)16例。比较两组患者颅内动脉(A组:198支,B组176支)、颅外动脉(A组:176支,B组128支)狭窄情况;又比较两组患者颈动脉系统(A组:180支,B组160支)、椎-基底动脉系统(A组:90支,B组80支)狭窄情况。结果①A组患者颅内-外动脉狭窄性病变的检出率分别为4.6%(9/198)及13.2%(19/144);B组分别为12.5%(22/176)及28.9%(37/128),两组比较差异均有统计学意义(P=0.005,P=0.001)。②A组患者颅内-外动脉狭窄程度分别为:轻度狭窄11支(39%)、中度狭窄9支(32%)和重度狭窄或闭塞8支(29%);B组分别为13支(22%)、14支(24%)及32支(54%),两组间重度狭窄或闭塞性病变比较,差异有统计学意义(P=0.026)。③A组患者颈动脉系统和椎-基底动脉系统狭窄性病变的检出率分别为8.3%(15/180)和8.9%(8/90);B组分别为21.9%(35/160)及16.3%(13/80),两组间颈动脉系统狭窄性病变差异有统计学意义(P=0.000);而椎-基底动脉系统狭窄性病变差异无统计学意义(P=0.147)。结论在冠心病患者中,冠状动脉狭窄程度越重,颅内-外动脉粥样硬化狭窄性病变亦越重,在颈动脉系统表现更加显著。
Objective To investigate the relationship between intracranial or extracranial arteriosclerotic stenosis and coronary artery stenosis. Methods A total of 34 patients with coronary heart disease, whose coronary artery stenosis were confirmed by coronary artefiography. All of the patients were underwent cerebral angiography simultaneously and were divided into group A （n = 18; coronary artery stenosis ≤ 2 branches） and group B （n = 16; coronary artery stenosis ≥3 branches）. Stenotic lessions in intraeranial arteries （198 arteries in group A; 176 arteries in group B）. extraeranial arteries （176 arteries in group A; 128 arteries in group B）. carotid artery system （180 arteries in group A; 160 arteries in group B） and vertebra-basilar artery system （90 arteries in group A; 80 arteries in group B） in both groups were compared according to their angiographie findings. Results Thedetectable rates of intra and extraeranial artery stenoses in group A were 4. 6% （9/198） and 13.2% （19/144）, respectively; and they were 12. 5% （22/176） and 28. 9% （37/128）, respectively in group B, and there was statistical significance between the two groups （P =0. 005, P =0. 001 ）. The severity of intra and extraeranial artery stenosis in group A was as follows： mild stenosis 11 arteries （39%）, moderate stenosis 19 arteries （32%）, and severe stenosis 8 arteries （29%） ; and they were 13 （22%）, 14 （24%）, and 32 （54%） arteries in group B, and there was statistical significance between the two groups （ P = 0. 026）. The detectable rates of stenotie lesions in carotid artery system and vertebro-basilar artery system were 8. 3% （15/180） and 8. 9% （8/90） respectively in group A, they were 21.9% （35/160） and 16.3% （13/80） respectively in group B, and there was statistical significance between the two groups （P =0. 000）; however, there was no statistical signifieanee in vertebra-basilar artery system （P=0. 147）. Conclusion In patients with coronary hea
出处
《中国脑血管病杂志》
CAS
2007年第6期241-245,共5页
Chinese Journal of Cerebrovascular Diseases
基金
首都医学发展科研基金[2002-1018]
