摘要
目的评价三磷酸胞苷二钠(CTP)联合地塞米松综合治疗贝尔面瘫的疗效。方法64例贝尔面瘫病者被随机分成CTP联合地塞米松组(C+D组,n=32)和地塞米松治疗组(D组,n=32)。C+D组使用CTP治疗加地塞米松,D组为传统地塞米松治疗。两组同时加用维生素B、吸氧及抗病毒治疗。House-Brackman面神经功能分级系统作为面神经功能恢复等级的评判标准。结果治疗后3周末,C+D组有17例痊愈(53.1%),8例改善(25%);D组7例痊愈(21.9%),4例改善(12.5%);治疗后4周末,C+D组25例痊愈(78.1%),5例改善(15.6%);D组14例痊愈(43.8%),7例改善(21.9%),两组间疗效差异有统计学意义,C+D疗效显著优于D组。结论CTP联合地塞米松治疗贝尔面瘫疗效确切,无明显不良反应,能显著提高贝尔面瘫治愈率。
Objective To evaluate the outcome of treatment associated sodium cytidine triphosphate（CTP） with decaesadril on the patients with Bell＇s palsy. Methods Sixty-four patients with Bell＇S palsy were randomly divided into two groups, sodium cytidine triphosphate and decaesadril group （C ＋ D group, 32 cases） and decaesadril group （D group, 32 cases）. The patients in C ＋ D group were treated with CTP combined with decaesadril,and the patients in D group were treated with traditional therapy of decaesadril. House-Brackmann facial nerve grading system was used as a evaluating method of the outcome. Results Seventeen patients （53. 1%） recovered completely,8 patients recovered partially in the C＋P group as compared with 7 patients（21. 9%）, 4 patients （12.5%） in the D group （P〈0.05）after 3 week treatment,and 25 patients（78.1%） recovered completely,5 patients recovered partially in the C＋D group comparing with 14 patients（43.8%） ,7 patients （21.9%） in the D group （P〈0.05） at the end of 4 weeks. Conclusion The research shows obvious effect in therapeutics with CTP and decaesadril on the patients of Bell＇s palsy compared with the patient given traditional treatment.
出处
《重庆医学》
CAS
CSCD
2007年第12期1128-1129,共2页
Chongqing medicine
