摘要
目的:探讨不同方法测定类风湿因子(RF)的临床应用价值。方法:采用免疫速率散射比浊法和胶乳凝集法检测类风湿关节炎患者35例,非类风湿关节炎患者43例及健康体检者20例的血清类风湿因子。结果:免疫比浊法检测类风湿关节炎患者、非类风湿关节炎患者的RF阳性率分别为56.9%、23.3%,20例健康者无阳性结果,此法的诊断效率为74.5%;胶乳凝集法检测类风湿因子阳性率分别为74.3%、46.5%和20.0%,其诊断效率为66.3%。结论:两种检测方法仅能测定IgM-RF,胶乳凝集法检测类风湿因子的敏感性较免疫比浊法高,但特异性相对较低,诊断效率略低于免疫比浊法。
Objective： To investigate the significance of rheumatoid factor determination by using different methods. Methods： The level of serum rheumatoid factor was detected by the immunoturibidimetrie assay and latex particle agglutination test in 35 cases of rheumatoid arthritis, 43 cases of other diseases without rheumatical arthritis and 20 healthy controls. Results：The positive percent of the rheumatoid arithritis group, the group of other diseases and the control group was 56.9%,23.3% and 0,respectively by using the immunoturibidimetric assay;and 74.3%,46.5%and 20.0%,respectively by using latex particle agglutination test. The diagnostic efficiency by using the immunoturibidimetric assay and latex paiticle agglutination test was 74.5% and 66. 3% ,respectively, Conclusion ：Only IgM-RF can be detected by the immunoturibidimetric assay and latex particle agglutination test. Rheumatiod factor determination by the latex particle agglutination is more sensitive than that by the immunoturibidimetric assay,with lower specificity and lower diagnosis efficiency of the latex particle agglutination test compared with the immunoturibidimetric assay.
出处
《黑龙江医药科学》
2007年第3期27-28,共2页
Heilongjiang Medicine and Pharmacy
