摘要
目的：探讨经蝶垂体瘤切除术后低钠血症的临床过程及其特点。方法：回顾分析经蝶垂体瘤切除术后低钠血症患者11例。结果：经蝶垂体瘤切除60例，术后发生低钠血症11例（18．3％）。2例发生在术后第1天，其余9例发生在术后4～9d，属于迟发性低钠血症。血钠一般是先缓慢下降，而后大幅度降至最低点，平均124mmol／L（范围112～132mmol／L）。7例（64％）有头痛、恶心、呕吐、昏迷等合并症，但都短暂可逆。治疗主要包括限制液体入量和补充钠盐两方面。11例患者均在治疗后7d内血钠恢复正常。结论：经蝶垂体瘤切除术后低血钠症的临床过程其有一定特点。若及时发现，正确治疗，均可很快恢复正常。
Objective：To examine clinical course and characteristics of hyponatremia after transsphenoidal surgery for pituitary adenomas. Methods：Retuospectively examining 11 patients with hyponatremia, Which developed after transsphenoidal surgery for pituitary adenomas. Results：Sixty patients reviewed who underwent transphenoidal pituitary surgery, 11 patients （18.3%） were discovered hyponatremia. Two patients developed hyponatremia on the very first postoperative day following surgery. The remaining 9 patients developed hyponatremia with a few days between day 3 and day 9 after surgery,which was defined as delayed hyponatremia. Mean serum sodium showed a tendency towards a mild decrease on the first postoperative day,followed by a significant drop to the nadir 124 mmol/L（range112 132 mmol/L）. Seven patients（64%） reported headache,nausea,vomiting or emesis. ]But the symptoms were transient and reversible. Treatment consisted of water restrietion and salt supplement. In all patients,hyponatremia resolved within 7 days after treatments. Conclusion ：Hyponatremia after transsphenoidal surgrry for pituitary adenomas has its own characteristic. If discovered in time and treated propetly,patients would recover quickly.
出处
《临床医药实践》
2007年第1期9-10,共2页
Proceeding of Clinical Medicine
关键词
低钠血症
垂体瘤
经蝶手术
hyponatremis,pituitary adenomas,transsphenoidal surgery.
