摘要
目的:观察定眩胶囊对椎-基底动脉供血不足大鼠脑组织SOD活性和血清NO含量的影响。方法:60只SD大鼠随机分为6组,分别为假手术组、模型组、西比灵组和定眩胶囊高、中、低剂量组,除假手术组外均进行中医痰浊中阻和西医椎动脉受压双重模型造模,并给予相应治疗药物,比较治疗后各组大鼠脑组织SOD活性和血清NO含量。结果:定眩胶囊大、中剂量组脑组织SOD活性和血清NO含量均较模型组高,P均<0.05。结论:定眩胶囊可提高椎-基底动脉供血不足大鼠脑组织SOD活性和血清NO含量。
Objective: To observe the effect of Dingxuan Capsule to the activity of brain tissue SOD and the content of serum NO of vertebro- basilar artery insufficiency rat. Methods: Sixty SD rat were random divided to 6 group, that were sham operated group, model group, Flunarizine group and Dingxuan Capsule high,middle and low dose group. Except the sham operated group, making the model of stagnation of turbid phlegm in middle - Jiao of TCM and compression of vertebral artery, every group were given corresponding drug,and comparing the activity of brain tissue SOD and the content of serum NO. Resuhs-The activity of brain tissue SOD and the content of Dingxuan Capsule high and middle dose group were higher than model group, P 〈 0.05. Conclusion:Dingxuan Capsule can raise the activity of brain tissue SOD and the content of serum NO of vertebro- basilar artery insufficiency rat.
出处
《江西中医学院学报》
2007年第3期66-67,共2页
Journal of Jiangxi College of Traditional Chinese Medicine
关键词
定眩胶囊
痰浊中阻
椎-基底动脉供血不足
Dingxuan Capsule
Stagnation of phlegm - damp in middle - jiao
Vertebro - Basilar Artery Insufficiency