摘要
目的观察扶正抑瘤方对晚期非小细胞肺癌化疗毒副反应的减毒作用及其对肿瘤特异性生长因子(TSGF)水平的影响。方法将42例患者随机分为对照组(20例,采用单纯化疗治疗)和综合组(22例,化疗结合扶正抑瘤方治疗),21d为1个周期,两组均连续治疗2个周期。比较两组患者化疗通过率,毒副反应,生活质量,血清TSGF水平。结果综合组化疗通过率略高于化疗组,生活质量明显高于化疗组,化疗毒副反应小于化疗组,TSGF下降水平大于化疗组。结论自拟扶正抑瘤方能够改善晚期肺癌患者生活质量,能在一定程度上降低化疗的毒副反应,并协同化疗起到抑瘤的作用。
To observe the clinical effects of ＂Fuzheng Yiliu Decoction＂ on non-small cell lung cancer and TSGF. Methods Forty-two subjects were randomized into two groups： control group in which 20 cases were treated simply by chemotherapy and treatment group in which 22 cases were treated with chemotherapy plus ＂Fuzheng Yiliu Decoction＂, with two courses. The chemotherapeutic effects, adverse reactions, quality of life and TSGF were observed. Results More patients in treatment group could endure chemotherapy; the quality of life was better, adverse reactions less and TSGF lower in treatment group than in control group. Conclusion ＂Fuzheng Yiliu Decoction＂ can improve the quality of life and relive adverse reactions in patients with advanced non-small cell lung cancer.
出处
《上海中医药杂志》
北大核心
2007年第6期18-19,共2页
Shanghai Journal of Traditional Chinese Medicine
