摘要
目的:研究纳洛酮在高血压脑出血术后患者中的治疗作用。方法:随机分为纳洛酮组{22例。常规治疗+纳洛酮[0.3 mg/(kg.d)静滴]}和对照组(22例。常规治疗)。对比两组治疗后第1、3、7、10 d的格拉斯哥昏迷评分(GCS)、格拉斯格结局评分(GOS)、语言和运动功能评分。结果:纳洛酮组在第7、10 d的GCS高于对照组(P<0.05);随访6个月后,纳洛酮组GOS和语言功能评分均高于对照组(P<0.05)。结论:高血压脑出血外科手术后早期、大剂量使用纳洛酮能有效保护脑神经功能,并促进其恢复。
Objective： To study the clinical effect of naloxone given to postperative patients with hypertensive intracerebral hemorrhage. Methods. The patients were divided into the naloxone group（22 cases）and control group（22 cases）at random. The Glasgow Coma Scale（GCS）, Glasgow Outcom Scale（ GOS） and the language and movement function scores between two groups were compared. Results： The GCS in the naloxone group was higher than that in the control group at day 7, 10（ P 〈 0. 05）. After follow-up for 6 months, the GOS and the language function score in the naloxone group were better than those in the control group （ P 〈 0.05）. Conclusion： Large dose of naloxone can effectively protect the cerebral nervous system, and improve the recovery of cerebral nervous system.
出处
《汕头大学医学院学报》
2007年第2期105-106,108,共3页
Journal of Shantou University Medical College
关键词
高血压脑出血
外科手术
纳洛酮
hypertensive intracerebral hemorrhage
surgery
naloxone
