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铜离子转运蛋白家族与卵巢癌顺铂耐药关系的研究进展 被引量：1

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摘要 顺铂是临床上广泛应用的化疗药物之一,但是目前顺铂摄入、泵出细胞,在细胞内发挥作用以及细胞产生继发耐药的机制尚不清楚。近年,文献报道铜离子转运蛋白家族如ATP7B、ATP7A、CTR1等在顺铂进出细胞的过程中起着重要的作用,并且可能与顺铂耐药的产生密切相关。现将铜离子转运蛋白家族与卵巢癌顺铂耐药关系的研究进展作一综述。
作者 张英丽 鹿欣 丰有吉
机构地区 复旦大学附属妇产科医院
出处 《现代妇产科进展》 CSCD 北大核心 2007年第5期388-390,共3页 Progress in Obstetrics and Gynecology
基金 上海市科委基础研究重点项目基金资助(05JC14012)
关键词 铜离子转运蛋白家族 卵巢肿瘤 顺铂 药物耐受
分类号 R737.31 [医药卫生—肿瘤]
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参考文献17

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同被引文献14

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现代妇产科进展
2007年 第5期

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