摘要
目的分析立体定向放射疗法（SRT）治疗脑转移瘤的临床疗效。方法回顾性分析66例脑转移瘤全脑放射治疗（WBRT）追加SRT和26例脑转移瘤单纯SRT的结果,分析两者在Karnofsky评分、颅内肿瘤复发率、一年生存率等方面的状况。结果WBRT＋SRT组在颅内肿瘤复发率（13.3%和42.2%）、中位复发时间（10.5个月和4.2个月）、中位生存期（13.0个月和6.5个月）与单纯SRT组相比有显著性差异（P〈0.05）,但在Karnofsky评分、治疗有效率、一年生存率、死亡率的差异均无统计学意义。结论WBRT＋SRT能明显改善患者的生存质量,降低肿瘤颅内复发率,是脑转移瘤的一种理想局部治疗手段。
Objective To investigate the effect of stereotatic radiotherapy （SRT） for brain metastases, Methods Retrospect compare 66 patients treated by SRT with whole brain radiotherapy （WBRT＋ SRT） to 26 patients treated by SRT alone, Results The patients treated by WBRT＋ SRT had significantly benefit in lesions recurrence （13,3% vs 42.2%）, middle recurrence time （10.5 months vs 4.2 months） and middle survival time（13 months vs 6.5 months） over the patients treated by SRT, respectively （P〈0.05）, But there are no different in terms of improving of Karnofsky score, effective rate, one-year survival rate, one-year death rate between the two groups. Conclusion WBRT＋ SRT play an important role in treating brain metastases, by improving patients＇ life quantity and reducing recurrence.
出处
《国际放射医学核医学杂志》
2007年第2期122-124,共3页
International Journal of Radiation Medicine and Nuclear Medicine
关键词
脑转移瘤
立体定向放射治疗
全脑放射治疗
Brain metastases
Stereotatic radiotherapy
Whole brain radiotherapy
