摘要
目的探讨相关因素对胃癌术后复发死亡的影响,为改善个体化综合治疗、提高术后生存率提供依据。方法回顾性分析2000年8月-2006年9月间胃癌根治术后复发者138例,其中死亡112例,对可能影响术后复发死亡的14项临床、病理和治疗措施,采用Logistic进行单因素和多因素回归分析。结果138例平均复发时间为术后19.8个月,2年内复发率76.8%,2-5年内复发率21.7%,5年后复发率1.4%;单一复发占81.9%,多种复发类型占18.1%;其中腹膜复发占49.3%,血行转移复发占34.8%,区域局部复发占15.4%;logistic单因素、多因素回归分析显示：病程分期、TNM分期、术后腹腔化疗、术前介入化疗是影响术后复发死亡的独立因素,其中腹腔化疗、介入化疗是保护因素。结论胃癌根治术后复发大部分发生在术后2年内,影响术后复发死亡的原因由多方面促成,独立因素起主要作用。
Objective To analyze the impact of relevant factors on recurrent death of gastric earinoma after curative resection and provide reference for individualized chemotherapy and enhancement of survival rate. Methods The clinicopathologic and follow - up data of 138 recurrent gastric earinoma patients after curative resection in Shimen County People＇s Hospital from August 2000 to September 2006 were analyzed. Results The average recurrent time was 19.8 months , being 76.8 % of them recurrent within 2 years after surgery, 21.7% recurrent in 2-5 years, 1.4% recurrent in 5 years. Conclusion Most of the recurrent of gastric carcinoma after surgery are within 2 years. The independent factors associated with the recurrent death are phasing of the disease, TN phasing, chemotheray by intraperitoneal and preoperative intraperitoneal infusion.
出处
《中国热带医学》
CAS
2007年第6期964-965,968,共3页
China Tropical Medicine
关键词
胃癌
复发死亡
相关因素
Gastric carinoma
Recurrent death
Relevant factors
