摘要
目的了解恶性肿瘤患者发生医院感染常见病原菌及耐药性,为临床合理使用抗菌药物提供依据。方法对2003年1月-2005年10月住院的恶性肿瘤医院感染患者临床标本中分离出的1 204株病原菌分类、药敏试验结果进行回顾性分析。结果1 204株病原菌G+菌占31.1%、G-菌占52.8%、真菌占16.1%;白色假丝酵母菌、大肠埃希菌、金黄色葡萄球菌、肺炎克雷伯菌、铜绿假单胞菌为主要感染菌,感染部位以呼吸道、泌尿道、皮肤软组织为多见。结论在治疗感染性疾病时应进行病原学检查,依据药敏试验结果合理使用抗菌药物,以减少耐药菌株的产生。
OBJECTIVE To evaluate the commonly encountered pathogens and drng resistance of bacteria causing secondary infection in patients with malignant tumors and provide reference for clinical antimicrobial usage. METHODS Statistical analysis was made retrospectively in the classification and antimicrobial susceptibility testing in 1 204 strains of pathogens isolated from clinical samples of hospitalized patients with malignant tumors from Jan 2003 to Oct 2005. RESULTS Among 1 204 strains, Gram-positive strains accounted for 31. 1% Gram-negative ones accounted for 52. 8% and fungi accounted for 16. 1%. The principal strains were Candida albicans, Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The most frequent infection sites were in respiratory tract, urinary tract and skin-soft tissue. Multiple drug resistant rate of Gram-positive and Gram-negative strains had a tendency of elevation. CONCLUSIONS To reduce the coming of drug resistant strains, etiologic examination should be done in treatment of infectious diseases and antimicrobial therapy should be decided according to the results of susceptibility.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2007年第6期660-662,共3页
Chinese Journal of Nosocomiology
关键词
病原菌
耐药
医院感染
Pathogen
Drug resistance
Hospital infection
