摘要
目的:了解氟伏沙明治疗儿童少年强迫症的疗效和安全性。方法:用CCMD-3作为诊断标准,将在我院诊断明确的8～16岁的60例儿童少年强迫症患者随机分成2组,分别给予氟伏沙明和氯丙咪嗪治疗,共观察8周,采用Y?BOCS和TESS量表评定临床疗效和药物不良反应。结果:氟伏沙明治疗儿童少年强迫症的总有效率为90%,氯丙咪嗪治疗儿童少年强迫症的总显效率为86.7%,两者无显著性差异;氟伏沙明不良反应发生率33.3%,氯丙咪嗪不良反应发生率70%,两者有显著性差异,且氟伏沙明的不良反应较轻。结论:氟伏沙明对儿童少年强迫症的治疗有很好的疗效,且不良反应少。
Objective：To observe the effects and security of Fluvoxamine and Chlormipramine in treating patients with Child - Adolescence Obsession. Methods： According to CCMD - 3, 60 patients with Child - Adolescence Obsession were randomly divided into Fluvoxamine and Chlormipramine group. The duration of treatment was 8 weeks. Yale - Brown scale and Tess were used to evaluate the efficacy and adverse effects respectively. Results ： The effective rates of Fluvoxamine group and Chlormipramine were 90% and 86. 7%, which showed no significant difference between the two groups. The occurred rate of adverse effects of Fluvoxamine group and Chlormipramine were 33.3% and 70%, which showed significant difference between the two groups. Conclusions： Fluvoxamine has good efficacy in treating Child - Adolescence Obsession, but has less adverse effects.
出处
《中国民康医学》
2007年第11期438-438,440,共2页
Medical Journal of Chinese People’s Health
关键词
儿童少年
强迫症
氟伏沙明
氯丙眯嗪
Child- Adolescence
Obsession
Fluvoxamine
Chlormipramine
