摘要
目的探讨24例原发喉部的非霍奇金淋巴瘤(non-Hodgkin’s lymphoma,NHL)的临床表现、病理、治疗及预后。方法 24例喉原发 NHL 中,声门上区19例,累及声门上区及声门区3例,声门区2例,病理均为非霍奇金淋巴瘤。全部病例均采用钴-60γ射线予局部放疗;20例子全身化疗,其中17例放疗前后以 CTX+VCR 方案化疗1～10个疗程,3例坏死型以司莫司汀口服。结果 1,3,5年生存率分别为79.2%,70.8%,70.8%。死亡7例,其中4例死于局部复发,2例死于小肠受累,1例死于肺浸润。结论放射治疗喉原发非霍奇金淋巴瘤预后较好,局部控制作用良好,是喉 NHL 的首选治疗方法。合理的化放疗及化疗方案值得进一步研究。(中国眼耳鼻喉科杂志,2007,7:160-161)
Purpose To study the clinical and pathological characristics, treatment and prognosis of primary laryngeal non-Hodgkin lymphoma（NHL）. Methods The data of 24 cases with NHL that were confirmed with pathology were retrospectively analyzed. Of the 24 cases, the lymphoma were located in supraglottic region in 19 cases, glottic region in 5 cases. All the patients were treated with radiotherapy with ^60Co γ rays locally. Twenty patients additionally received chemotherapy. Results The overall 1-, 3- and 5-year survival rates were 79.2%, 70.8%, 70.8% respectively. Seven patients are dead. Conclusion The prognosis of primary laryngeal non-Hodgkin lymphoma is generally fine. Radiotherapy can control the lymphoma to prevent from metastasis. It is a satisfactory remedy for treatment of NHL.
出处
《中国眼耳鼻喉科杂志》
2007年第3期160-161,共2页
Chinese Journal of Ophthalmology and Otorhinolaryngology
关键词
喉肿瘤
放射疗法
非霍奇金淋巴瘤
治疗
laryngeal neoplasms
radiotherapy
non-Hodgkin＇ s lymphoma
therapy
