摘要
利用存在缺陷的LB膜来模拟受损伤的肾上皮细胞膜诱导肾结石矿物草酸钙(CaOxa)晶体生长.经2.5mmol·L^(-1)的草酸钾溶液对二棕榈酰磷脂酰胆碱(DPPC)的LB膜进行处理后,可强化LB膜中液态扩张相(LE)和液态凝聚相(LC)之间的结构差异,原子力显微镜(AFM)证实了圈状缺陷的存在.以LB膜的圈状缺陷为模板,诱导了一水草酸钙(COM)晶体环状图案.相比之下,未经草酸钾处理的LB膜只诱导生成零散的六边形COM晶体.
Defective LB film was used as model for injured renal epithelial membrane to induce the growth of calcium oxalate monohydrate （COM） crystals, which was the major inorganic component found in renal calculi. After the LB film of dipalmitoylphosphatidylcholine （DPPC） was treated by 2.5 mmol·L^-1 potassium oxalate, the structural differentiation between liquid expanded （LE） phase and liquid condensed （LC） phase in LB film was strengthened and circular defects appeared. These circular defects were proved by atomic force microscopy （AFM）. Such circular defects could induce ring-shaped patterns of COM crystals. In comparison, the LB films without pretreatment by potassium oxalate only induced randomly growth of COM crystals.
出处
《物理化学学报》
SCIE
CAS
CSCD
北大核心
2007年第5期713-716,共4页
Acta Physico-Chimica Sinica
基金
国家自然科学基金(20471024)
教育部留学回国人员科研启动基金(教外司[2005]55号)资助项目
关键词
缺陷LB膜
生物矿化
草酸钙
AFM
Defective LB Film
Biomineralization
Calcium oxalate
AFM
