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类风湿性关节炎自身抗体试验的比较

Comparison of the 5 Methods for Detecting Autoantibody in Rheumatoid Arthritis
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摘要 目的比较类风湿性关节炎(RA)的5种自身抗体检测的诊断性能。方法检测64名RA患者(急性期28名,慢性期36名),30名其他风湿性疾患患者和30名健康体检者的5种自身抗体。结果统计5项试验的诊断性能相关指标,结果5种自身抗体以ACCP和ACⅡ为最好。试验的诊断准确性依次为ACCP>ACⅡ>AKA=RF>ASa。结论RF定量可作为RA的筛查试验,最好并用RF和ACCP或ACⅡ其中之一。 [ Objective ] To compare the diagnosing function of 5 methods for detecting autoantibody in rheumatoid arthritis. [ Methods] 64 RApatients (28 in acute phase, 36 in chronic phase ), 30 patients of thematic diseases, 30 healthy people were tested for 5 antibodies. [ Results ] The relevant indexes of the statistics of the 5 testing methods showed that ACCP and AC Ⅱwere proved to be the best among the 5 autoantibodies; the order of diagnosis accuracy was as below: ACCP 〉 AC Ⅱ 〉 AKA = RF 〉 ASa. [ Conclusion] RF quantitative can be used as screen test; it is suggested to combine it with ACCP or AC Ⅱ.
作者 李延博
出处 《职业与健康》 CAS 2007年第12期998-999,共2页 Occupation and Health
关键词 类风湿性关节炎 自身抗体 诊断性能 Rheumatoid arthritis Autoantibody Diagnosing function
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