摘要
目的探讨内镜黏膜切除术(endoscopic mucosal resection,EMR)在胃黏膜及黏膜下病变中的应用,分析该方法的优势及治疗效果。方法对常规胃镜活检未能确诊的8例胃黏膜及黏膜下病变行EMR送活检。12例早期胃癌,8例行EMR治疗,4例行手术切除治疗,术后定期复查胃镜及随访调查。结果8例行EMR病人,诊断出早期胃癌3例,浸润型胃癌2例,胃黏膜相关淋巴瘤2例,克罗恩病1例。8例行EMR治疗的早期胃癌,随访6年1例,4年1例,1~3年5例,病人无肿瘤复发均存活,1例3个月后复查胃镜随访发现有另一病灶而行手术治疗,4例行手术治疗的早期胃癌病人,随访存活5年2例,存活1年1例,1例病人死亡。结论常规胃镜活检未能明确诊断的病人,经EMR可以达到明确诊断的目的。在早期胃癌阶段对病人实施治疗可明显提高患者存活率。EMR治疗不失为一种疗效确切、安全、痛苦小、经济的治疗方法,值得大力推广。
[Objective] To assess the diagnostic and therapeutic efficacy of EMR. [Methods] Eight patients given EMR for diagnosis were summed up. Twelve patients with early gastric cancer, in which eight cases were given EMR, four operations, all the patients were periodically followed up with endoscopic examination. [Results] The histology of EMR revea/ed in early gastric cancer in 3, gastric cancer in 2, gastric lymphoma in 2, crohn disease in 1. Eight patients with early gastric cancer given EMR were not given chemotherapy, only one patient recurred cancer and was given operation, all the patients were still survived, the longest period was six years. [Conclusion] EMR, a facile and useful diagnostic and therapeutic technique. The treatment on the early stage of gastric cancer can raise patients' survival rate. EMR is a safe, effective, economical method and there is minimally invasive procedure. EMR is worth extending.
出处
《中国内镜杂志》
CSCD
北大核心
2007年第5期486-488,共3页
China Journal of Endoscopy
关键词
黏膜切除术
早期胃癌
mucosal resection
early gastric cancer