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氟康唑治疗新型隐球菌性脑膜炎3例报告 被引量:2

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摘要 例1,男性,30岁,农民,主因头痛、发热1个月于1995年8月24日入院,既往有系统性红斑狼疮史。3个月前复发,口服强的松30mg/日。1个月前出现后枕部头痛,发热,体温在37.5℃~38.9℃,伴恶心,呕吐。半月前行腰穿检查,脑脊髓(CSf)压力3.92kPa,涂片查到新型隐球菌,给予氟康唑首次剂量400mg/日,之后200mg/日,14天后仍间断头痛,转住我院。查体:Bp25/16kPa,贫血貌,“满月脸”,面部可见对称性蝶形红斑,腹水征(十),双下肢水肿。神经科查体:神清,语畅,双眼视乳头水肿,颈抵抗(+)。继续静点氟康唑每日200mg。1周后主诉视物不清,查双眼视盘边界不清,其周围网膜水肿,有小片状出血,治疗13天疗效不显著,自动出院,一周后死亡。
出处 《脑与神经疾病杂志》 1997年第2期121-121,共1页 Journal of Brain and Nervous Diseases
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  • 1史玉泉.实用神经病学[M].上海:上海科学技术出版社,1995.293-299. 被引量:93
  • 2曾庆馀,宗淑杰.新型隐球菌性脑膜炎的治疗体会——附22例临床分析[J]实用医学杂志,1985(05). 被引量:1
  • 3H. Yamaguchi,H. Ikemoto,K. Watanabe,A. Ito,K. Hara,S. Kohno.Fluconazole monotherapy for cryptococcosis in non-AIDS patients[J]. European Journal of Clinical Microbiology & Infectious Diseases . 1996 (10) 被引量:1
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