摘要
0．1moL苯胺用80．0mL溶剂溶解后，以无水AlCl3为催化剂，以溶解于30mL溶剂中的氯代异丙烷为烷基化试剂，通过Friedel—Crafts反应合成了对异丙基苯胺；用元素分析、FT—IR和^1H NMR的方法对所得产品的结构进行了表征。结果表明：1，2-二氯乙烷是合适的反应溶剂；在烷基化反应温度为6～10℃、反应时间为75～105min、无水AlCl3对苯胺物质量的比为1．1～1．2、氯代异丙烷对苯胺物质量的比为1．1～1．2时，对异丙基苯胺对苯胺的收率可达70％左右。
After 0.1 mol aniline had been solved by 80.0 mL solvent, aluminum chloride anhydrous as catalyst , isopropyl chloride which was solved in the 30.0 mL solvent previously as alkylating agent, 4 - isopropylaniline was synthesized through Friedel - Crafts reaction. The product was determined by elementary analysis, FT - IR and HNMR. The experimental result indicated 1,2 - dichloroethane was the suitable solvent. When the reaction temperature was 6.0 to 10.0℃, the reaction times were 75.0 to 105.0 minute, the molar ratio of aluminum chloride anhydrous to aniline was 1.1 - 1.2 and the molar ratio of isopropyl chloride to aniline was 1.1 - 1.2, the yield of 4 - isopropylaniline could up to 70%.
出处
《化学工程师》
CAS
2007年第5期13-15,共3页
Chemical Engineer
