摘要
目的探讨术前经动脉新辅助治疗对进展期结直肠癌的临床价值。方法在DSA治疗平台上,经股动脉置入导管,超选择进入肿瘤供血动脉注入化疗药物和栓塞剂,治疗结直肠癌共47例,治疗后7-12 d手术。观察病人症状变化,判断疗效及术中癌灶和其周围组织情况,并了解病理所见。结果病人症状减轻,疗效明显,瘤体缩小,癌肿降期,易于切除,癌细胞部分变性坏死。结论进展期结直肠癌术前经动脉新辅助治疗临床疗效显著。
Objective To explore the clinical results of neoadjuvant therapy by artery in preoperative patients with advanced colorectal carcinoma. Methods In DSA curing platform, the catheter was introduced into artery to perform angiography. Superselective intra - arterial chemotherapy and embolization treated 47 cases of colorectal carcinoma. 7 -12 days later, surgical operations were done. Observing the patient＇s symptom changes and surgical pathologic findings, judging curative effect. Results 43 cases＇ symptoms （colica, fullness and hematochezia, et al. ） were obviously subsided before surgical operation. No one deteriorated. 41 patients /tumor diameter was reduced and cancerous protuberance easy to operate. Dukes stages were abased. Cancer cell＇s partial denaturation and cytoclasis were observed under microscope. Conclusion Neoadjuvant therapy （superselective intra -arterial chemotherapy and embolization） is a feasible, safe and effective technique for treating advanced colorectal carcinoma. Treatment group show better result.
出处
《中原医刊》
2007年第10期22-23,共2页
Central Plains Medical Journal
关键词
结直肠癌
动脉
新辅助治疗
Colorectal carcinoma
Artery
Neoadjuvant therapy
