摘要
Novel macrocyclic polyamine La(III) complexes have been synthesized.The hydrolysis of plasmid DNA(pUC18) by macrocyclic polyamine La(III) complexes has been investigated by using agarose gel electrophoresis method.The results indicated that these La(III) complexes could effectively promote the cleavage of plasmid DNA(pUC18) at physiological pH and temperature.
Novel maerocyelie polyamine La（Ⅲ） complexes have been synthesized. The hydrolysis of plasmid DNA （pUC18） by maerocyelie polyamine La（Ⅲ） complexes has been investigated by using agarose gel eleetrophoresis method. The results indicated that these La（Ⅲ） complexes could effectively promote the cleavage of plasmid DNA （pUC18） at physiological pH and temperature.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2007年第5期539-542,共4页
Chemical Research and Application
基金
国家自然科学基金资助项目(20372051
20471038
20572075)
教育部新世纪优秀人才资助计划项目
教育部博士点专项基金资助项目
四川省青年科技基金资助项目
关键词
大环多胺
配合物
DNA水解裂解
macrocyclic polyamine
complexes
hydrolytic cleavage of plasmid DNA
