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临床X射线相衬成像的实现 被引量:5

Clinical X-ray phase contrast imaging
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摘要 目的提高人体软组织成像的衬度分辨率及空间分辨率,实现其在临床诊断方面的应用。方法在物理上采用相衬观察法,即附加一些光学装置和某些其他特定条件将相位分布转换成强度分布。而在数学上,则通过傅立叶变换和卷积处理得到其强度分布的数学表达式。结果类同轴全息X射线相衬成像是极有可能应用于临床的一种相位成像方法,并具有广阔的应用前景。结论实现临床X射线相衬成像需要解决相干光源和光源与样品之间及样品与探测器之间距离这样的两个关键技术问题。 Objective To improve the spatial resolution and the contrast resolution of human soft tissue imaging for application in clinical diagnosis. Methods In physics, the phase contrast observation was adopted by means of adding optical elements and other special conditions that could transfer the phase distribution to intensity distribution. Then the mathematical formula about intensity distribution was obtained by Fourier transform after and Convolution theorems. Results Among the three methods introduced in the paper,the in-line X-ray phase contrast imaging was one of the great probability to be applied in the clinic diagnosis. Conclusion In realizing the application of X-ray phase contrast imaging ,the coherence light source and distances (including the distance between source and object,and the distance between object and detector) are considered as two key technical problems to be solved.
作者 刘松 张学龙
出处 《生物医学工程与临床》 CAS 2007年第3期167-170,共4页 Biomedical Engineering and Clinical Medicine
基金 上海市重点学科(P0502) 上海市高校科技发展基金(07ZZ93) 上海市重大科研项目基金(06DZ11311) 河南省自然科学基金(0611051500)
关键词 类同轴相衬成像 衬度分辨率 微聚焦X射线管 in-line X-ray phase contrast imaging contrast resolution micofocus X-ray tube
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参考文献12

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