摘要
目的:从幽门螺杆菌(H.pylori,Hp)感染角度探讨ABO血型对十二指肠溃疡(duodenal ulcer,DU)发病的因素。方法:比较80例DU患者组和1061名健康对照者血型分布的差别及DU组不同血型发病年龄。利用快速尿素酶实验Hp测定仪检测,确定DU组不同血型者Hp感染率并进行比较。结果:DU组O型血者占56.3%,高于O型血在正常人群中的分布28.7%(P<0.005),不同血型者DU平均发病年龄差异无统计学意义(P>0.05)。DU组不同血型者Hp感染率差异无统计学意义(P>0.05)。结论:O型血者易患DU不是通过Hp感染或胃酸分泌来起作用的。
Objective：To clarify the relationship between blood group ABO and duodenal ulcer（DU） in patients with H. pylori（Hp） infection. Methods：The blood type of 80 patients with DU and 1 061 healthy controls were determined. The age of disease onset in DU patients with different blood types was compared and the Hp infection rate was determined by rapid urinase test. Results：Fifty six point three percent of the patients in DU group were of blood group O, which was significantly higher than the normal blood group distribution rate（28.7% ） in healthy population （P 〈 0.005 ）. However,there was no statistical difference in the average age of disease onset or in the Hp infection rate（P 〉 0.05 ） among different blood groups. Conclusions-Patients with blood group O doesn＇t acquire DU by Hp infection or stronger gastric acid secretion.
出处
《蚌埠医学院学报》
CAS
2007年第3期312-313,共2页
Journal of Bengbu Medical College
